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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa12eb4dc68f77d944e4e2c18d8bfe069a6e1885d62569c485df02e1759fc648' 
  AND token = 'hqrDY9lqbU9d/EhuGPKr9rCrUaV25xFC22N47H3sogY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}