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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb3f4eaea631443f7c6d5c4973e0dd0367e1ac7339496cfc4d51e1c86dfca8b9' 
  AND token = 'uV+EG/WyDRbdN/X6BgU54nhhTuv9VTvSsTC0Xh6pXH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}