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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bbd3f258505a406250969fe2c3261a898738bd9ec03bc8229213b82e3cc221c' 
  AND token = 'Co2MVKP5MPGVa+V76ZX07q8XGh/n7g6QSqa49M+nJ3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}