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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66484d9664db3a2deecc83f6eefc1834c6531d96566f0a57b8cb7fba938da3ad' 
  AND token = 'K+xPReSu0gs/qspQwU2ogTpo1Ig6r9crdro5Ha6BCf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}