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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e38b1f228210e60029d056a1ee9e8b20ef64187a7a2757eb2c5da4522e781db' 
  AND token = 'NaYJ3NN6kLSt2ksNgKLGI47zl1ZSNYIUlTEqg+xZxP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}