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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c519daafb9270e10caef1554ffba4ec2c3c124032dc72797325274d1b467e8bf' 
  AND token = 'QFaaql/pqNpm2C1o6TE5txSfrnLgZZzuEfAdCNTWuLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}