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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c364f4a0ec1d64213d9f6f6572542c91ad9717f881c6f8d538d976e45de9783c' 
  AND token = 'KqpnT4tqvTRZI72hYQrT8UuBg/YdSz1KeDE17nDyb44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}