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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '940bbc6151b17b3620c053364c55b9fff9326c7db132fca60d6303da471fecd6' 
  AND token = 'Q25fGGvmmBQot6FpK2b9/RIBcN9KPiGx7UhRDUkMh5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}