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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a1866445afb699803eb589e7a0e2cd9d04d77eb35e14cca67913297aeeacdcd' 
  AND token = 'Qjg8JvRfwWA6dvsVxs46EeiJ2vzDmXhW2RPoXX1rddE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}