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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee8682995adb3b63b8ff0f15a4971c358ca5b36c1d474e6cc1523427c2691a96' 
  AND token = 'HOMtbZrs9WtYsFQM9R6SHsRcdp6mbyZshRQm+d7pMeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}