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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5cba565e57259102d5c5c48d20bac0af86c5cda315f64725dc32ba714f3c465' 
  AND token = 'IQ0j4GNjjoy6HCmRpCIf3YvKsFSzbRVPPbs5npqR2LI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}