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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c8a3935189f3ea4e0ead9b78bf4453913702bcf7832b610e6d321695a965d30' 
  AND token = 'XrR7F6lf46YaPgnmowkCMvV298xB2dE78SsX2B4MaWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}