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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a2287e42526285a801cd769ae75fc2eaca48eabaf74d94e04bbe3ad2c45f3cf' 
  AND token = 'CqcVVHnSdRkq6EdpRbKSMQ4EdQyDxPP5Y9yhkjQLPDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}