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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de919166880a58a1f2afd05002e26eb5f619b5d70029290017547d1f6d1e8688' 
  AND token = 'UB41ZbBmwxSEH7tHkA2FlFlkmGIxIxoi/KTKlMvXOXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}