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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8164296b14102845a1174a10f35c37810523ee2af6fb746caf562f27dd1fa64' 
  AND token = 'BYgY5TtdeQ3NTSOObzFRIC37A6eyZ3IK4brSiZ3Fnek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}