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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eb5782deb04b7bc8227b5d2f855595d5ba3e3ccbdc6260303d747e21cf87efb' 
  AND token = 'u9Q/HrSSsK3/vltu4N1BKvbRRaxWa28sXU1aRvAaj+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}