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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fef2827d303d5b0aeeda31c9b9a535788a511d5cfa48016b5b6da4efc2fff790' 
  AND token = 'oO8E9Zkav02d18j2Y7Z8P2P9e9wcDzGB/3B92DuOv+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}