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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cf67e166b7896f61c440da3c64d11b58daf09b1960afc89aabe2e8df3d387be' 
  AND token = 'sX/URO6J+olUQTHnRzu5Q8SfUouEUb7H4oLN56YARhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}