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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49c402fe6d3ac203267884efaa90022fa6be0daf006084f04d38ced177e40e7' 
  AND token = 'KTPrNmRvIcdPRho8EJgZ/DUNiTzTYgNn++pxR2P2lKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}