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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a1aedf0e6e77b63524fde58acdabb4edcb91b73ab798ba3e3b2c287f5b7330c' 
  AND token = 'XQArR5pDcEcrIljQIH2Av5FG9DiaSQsS3E+8Sm/LMqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}