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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6eeb72b140deee22ddb908064f55246db9a65a59b427847534b60696223af55' 
  AND token = '0X1bqZFT83W5aUcMp2KdnGqIlD9fZz7l+R4TytevjaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}