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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09bbe27c54a23ed13caaaeaf41ccfe90c7bd384f5050e21a857dd9199117fa74' 
  AND token = 'ciWNklh4/mPk+Gyo8TjKqrVxMD3xNusDxw+tXBmo/oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}