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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44d03a134ef18922837d1373a96874f9385d4e3b883c84d50103394e7f07f2c4' 
  AND token = 'tbBU4jFG0cvCbsGpC2d3gQAbMp703mF4AeUBYiBG8uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}