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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1bc923ecda878eaf0bfa563e60799ef0464ca4f4aa1e1e2e559f6a7ac580cbd' 
  AND token = 'BH4LGPN9iuJbZCt5tRz1bEKymGlDVVo2eDrKuqu2Kos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}