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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc855aea674543da770a0a0d11fefde0c3c278c5641e2fa4ead3872ed8c8766' 
  AND token = 'EA+CAnT3CUuzBWIugjpQVAvr5igQXGzA2ZaeGs0Fdno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}