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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '170e77a178b74366bb22e0b4eb3cada3faeb776e282502b2fdf21532a8fe3fec' 
  AND token = 'W39M++KvPqCsEUQXotK+Dt/h/hvZyyFsZo0RF7dTC24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}