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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc4e2365e28aab3313953cc0c3d41d37fc60aa26815b93ef508f0f9cc73b7bd9' 
  AND token = 'DmcjY6+wia/pnIo5QxQRiP9nffZ0stTCX0K1+pFOYZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}