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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '197d185e03a6a58ca8203e693ba94ced28769dfdcab2c4956513796217cf7ae8' 
  AND token = 'qwyftsxKtLquvyK2emPYOKogRmEahkRKK93cz+xYRLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}