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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '046378b3331912a6969a2217a95a229bfe2568405d636275697d47d3b86b0919' 
  AND token = '4knJ0F6JYOiu1sK7jj+S9YZQrFS/PHwXEQkKfI5b+b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}