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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e201449dd4501754f9da7ceb000ec66ed0d816fb44c91cfcc6b2b54591feb5d7' 
  AND token = 'EUnsNQRFLeQiqq4myOxBAstmQNyzAJSunG9DJqOuAu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}