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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d8c8ceab8d589de6a82f84edc503492ce93195ab2f725325fd6e6f48ec10ab' 
  AND token = 'OQuwA6vkZPSqjbuYWgpqtkL5t6xI+AwUpAfC4bB5upo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00121

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}