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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a07b7a921d159e6efa461e7c4a6dcd1ace07161608f3902ed0dc2b0cb59c027' 
  AND token = 'HDr9LgjJZS4Ac4dO42qmFwBSOGDLNIn382Z+5gcPu2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}