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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4908e0433d9f4569513d10cc4402e40d3dfed82048e7911a9e5ab7f7df0ef405' 
  AND token = 'xJ6uhyQkbrGIOhE3NGai3ScNWFVEf0Fcbz2HzJIctt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}