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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '747ecc8e7dcc52b580c032a80578e3974174ab0d65954930185fc3e6cceda088' 
  AND token = 'wVkyTag1BjgaB9T96IObjrWBOBaNhY/OgjEjkFbZBTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}