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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0379bb503c9cb7696c6e2041c733eaa811b70e660b99222c5efc51d383d9a21' 
  AND token = '1wz8Ih7+/s10ytfkbWz+RvQVcVmcktX/NTt9BXDZcEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}