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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36fb3d2772764aef72af3d79a09b84018d371ead8e3dababdec9bfb638ff3b99' 
  AND token = 'cmyCru3DL8hpxrtv6pc9aKTDT+gF/viqpDj0TxsZ3qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}