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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b73e865afe5fcc954eb1ed72f2c9b5d324d90698171013ac5e1b36fed2fcbc' 
  AND token = 'eCyS+TvRkrTd+WeEH+SNgpAoF1Xrk0Bz3/K1CaLI3oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}