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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5245c562b8c69f57e14e9b25cc3957df9dee749eb16dccb0df871ee11fc1502' 
  AND token = 'Iqxf7j4N8p/Wb4YiDfdYa62crCKxzGEUF4UT4+2bDS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}