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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '247bd567865838d2e1a4ca0c5709147b94897a4eb0c9b10ab5bfcbad3c1d29a4' 
  AND token = 'OKQdDfROWmPi39GwwXD4Te3JmPTbPc2gyqXVZPpMpNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}