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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd23f9bc0b9044f5bb56d105374432c6e1156d452817c011b400a842dbb4391' 
  AND token = 'vtj2P4r+ORI0PtWk5XHBj1dVLWoouhsGRcsV6N0Z2NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}