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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4239ab18044dfa01390407640255f4ee372ab98cb30163d9fb10aec2da82f66' 
  AND token = '+NFeNc0V7j4skALVtPHWzsMFLhZewppnmI7xcfQhGP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}