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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bd6f1fe6165181b4edfb9f1731da6f026aeb6f5da8cbd008f530c62956259d2' 
  AND token = 'YuyLfhsQlvm4lTSfuXR905kFXv55oP2h/TutWhYK1mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}