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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dce33ccb02dabe6c30a800d9a40563523cb649f879b7f824e9533353a59cba3' 
  AND token = 'JY6Ex1/bSIUZohsG6nV7gJX/7icLWf/D8qsxf4Cd/qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}