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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666a5f46d8e052762861d07da0f47e766b34c7a09788c9dafd93e439c3002f09' 
  AND token = 'Cu564gGu+qIMXHnJNTpdaTfSfXDiWhHYfsrQLf/eCv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}