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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8bc64ecfe5e7b5a74e4fc1fd72cc5fc3e1fdd28af8f054373eb224ff5b2b446' 
  AND token = 'VLl90C2pu0dJ79b8VWu65N33QAsqRBP6xC8ABDPo7jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}