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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb733f8d8dea96186f48c81ffe84f88a54930f44746cbf24977613d81eaa10e5' 
  AND token = 'pdzCsz/lFQgVlI5ntf+d0vRgQYdOm6fXdbCgXcNzqvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}