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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aef50d347b4681da72846428c3e6b06deb4e76e79685154fc4f376b1f27ecfba' 
  AND token = 'Wjs45OjOdrKpWHnPsndENDeOaJzIGv78Bhm8ujivR6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}