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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '578c785f59a225433d177b0aeee2d99c1ca792f5157e4791339b59ed539332ad' 
  AND token = '9i7+P+VNCoSeasDMKEy9cgNbMMwa7y9lZpuknoKYZNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}