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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '275dfc0a53634be6634618e23a51a1031cb43726058f1a5279b09e5844ec096a' 
  AND token = 'SQn8vkbZABGDypwkNj7GEaGoh1rV3NZjyBosj8Si6XY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}