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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c271db4c4ae6dd3b448133793d04f72d2d21e2f22a93e07c389a01139c8b3aa' 
  AND token = 'jjB3W3617VgepGqYJSFY59qeyg6v76qQZ8L2B/3rQAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}